Description

Boc-D-Hse(Bzl)-Oh CAS NO 150009-60-2 is a protected, non-proteinogenic amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for introducing the D-isomer of homoserine with orthogonal protecting groups, enabling precise control over peptide chain assembly and modification. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of D-homoserine into custom peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including hormone analogs and enzyme inhibitors.
• Peptidomimetic Design: Serves as a scaffold for creating modified peptides with enhanced stability, bioavailability, or target specificity.
• Bioconjugation: The benzyl-protected side chain offers a handle for further chemical modification and linker attachment.
• Academic & Industrial R&D: Employed in chemical biology studies to probe protein function and structure-activity relationships (SAR).
• Production of Reference Standards: Used to synthesize high-purity analytical standards for quality control in peptide manufacturing.

Basic Information

Product Name	Boc-D-Hse(Bzl)-Oh
CAS No.	150009-60-2
Molecular Formula	C16H23NO5
Molecular Weight	309.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-homoserine benzyl ester; D-2-Amino-4-(benzyloxy)butanoic acid N-Boc derivative; Boc-D-homoserine(Bzl)-OH; tert-Butyloxycarbonyl-D-homoserine benzyl ether; (S)-2-((tert-Butoxycarbonyl)amino)-4-(benzyloxy)butanoic acid; Boc-D-Homoser(Bzl)-OH; N-Boc-D-homoserine benzyl ester
EINECS	Contact for details

Quality Control

Our Boc-D-Hse(Bzl)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.