Description

Methyl 2-Chloropyrimidine-4-Carboxylate is a high-purity, versatile pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, where the chloropyrimidine moiety and the methyl ester group enable precise molecular construction for complex target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring pyrimidine-based scaffolds.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Material Science: Potential intermediate for the synthesis of specialty chemicals, dyes, and functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	Methyl 2-Chloropyrimidine-4-Carboxylate
CAS No.	149849-94-5
Molecular Formula	C6H5ClN2O2
Molecular Weight	172.57 g/mol
Synonyms	2-Chloro-4-(methoxycarbonyl)pyrimidine; Methyl 2-chloro-4-pyrimidinecarboxylate; 2-Chloropyrimidine-4-carboxylic acid methyl ester; 4-Carbomethoxy-2-chloropyrimidine; 2-Chloro-4-pyrimidinecarboxylic acid methyl ester; Methyl 2-chloro-4-pyrimidinecarboxylate; 149849-94-5
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloropyrimidine-4-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, and custom synthesis can be performed to meet specific client requirements, including research-grade or cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.