Description

Xemilofiban CAS NO 149820-74-6 is a potent and selective non-peptide glycoprotein IIb/IIIa (GP IIb/IIIa) receptor antagonist. This compound is of significant interest in pharmaceutical research and development due to its mechanism of action in inhibiting platelet aggregation. It is primarily utilized by pharmaceutical companies and research institutions engaged in the development of novel anti-thrombotic and cardiovascular therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced antiplatelet drug candidates.
• Biochemical Research: Used as a reference standard and tool compound in studies of platelet function and thrombosis.
• GP IIb/IIIa Receptor Studies: Employed in vitro and in vivo to investigate the role of this integrin receptor in cardiovascular diseases.
• Drug Discovery Programs: A critical material for high-throughput screening and lead optimization in cardiovascular R&D.
• Clinical Research Material: Used in the preparation of formulations for preclinical and clinical trial stages.

Basic Information

Product Name	Xemilofiban
CAS No.	149820-74-6
Molecular Formula	C29H41N3O5S
Molecular Weight	543.72 g/mol
Synonyms	Ro 44-9883; L-703,014; (2S)-2-[[(3S)-3-[[[4-(Aminoiminomethyl)phenyl]amino]carbonyl]-2-oxo-1-pyrrolidinyl]carbonyl]amino]-3-(4-pentylphenyl)propanoic acid; Xemilofiban hydrochloride; SC-54684; L 703014; Ro 44-9883/001
EINECS	Contact for details

Quality Control

Our Xemilofiban is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.