Description

1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-Yl)-4-Oxo-Quinoline-3-Carboxylic Acid is a high-purity pharmaceutical intermediate of significant commercial and research importance. This compound serves as a critical building block in the synthesis of advanced fluoroquinolone antibiotics, enabling the development of next-generation antimicrobial agents. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on active pharmaceutical ingredient (API) production and novel drug discovery.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a core precursor in the synthesis of potent antibacterial agents, leveraging its quinolone-carboxylic acid structure.
• Active Pharmaceutical Ingredient (API) Development: Used in research and commercial-scale manufacturing processes for developing new antibiotic formulations.
• Pharmaceutical Research & Development: A vital compound for medicinal chemists exploring structure-activity relationships (SAR) and novel antibacterial candidates.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex molecules with targeted biological activity.
• Reference Standard: Used as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical production.

Basic Information

Product Name	1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-Yl)-4-Oxo-Quinoline-3-Carboxylic Acid
CAS No.	149676-40-4
Molecular Formula	C₁₇H₂₀FN₃O₃
Molecular Weight	333.36 g/mol
Synonyms	1-Ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; 1-Ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; 7-(4-Methylpiperazin-1-yl)-1-ethyl-6-fluoro-4-oxoquinoline-3-carboxylic acid; Gatifloxacin Intermediate; AM-1155 Intermediate; PD-135432 Intermediate; GTX Intermediate; Quinolone Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our 1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-Yl)-4-Oxo-Quinoline-3-Carboxylic Acid is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, supporting compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.