Description

3,3-Diphenyl-L-Alanine is a non-natural, chiral amino acid derivative featuring two phenyl substituents on the β-carbon. This unique structure makes it a valuable pharmaceutical intermediate and building block for advanced organic synthesis. It is primarily utilized in the research and development of novel peptide-based therapeutics, enzyme inhibitors, and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of peptide drugs and enzyme inhibitors targeting metabolic and neurological disorders.
• Peptidomimetics Research: Serves as a constrained, hydrophobic amino acid analog for designing bioactive peptides with enhanced stability and receptor affinity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in catalytic systems for the enantioselective construction of complex molecules.
• Chemical Biology Probes: Used to incorporate bulky, aromatic groups into peptides for studying protein-protein interactions and structure-activity relationships (SAR).
• Material Science: Potential monomer for synthesizing specialized polymers with unique optical or structural properties.

Basic Information

Product Name	3,3-Diphenyl-L-Alanine
CAS No.	149597-92-2
Molecular Formula	C15H15NO2
Molecular Weight	241.29 g/mol
Synonyms	(S)-2-Amino-3,3-diphenylpropanoic acid; L-3,3-Diphenylalanine; (S)-3,3-Diphenylalanine; β,β-Diphenyl-L-alanine; H-Diphenylalanine-OH; 3,3-Diphenyl-L-α-alanine; (S)-α-Amino-β,β-diphenylpropionic acid
EINECS	Contact for details

Quality Control

Our 3,3-Diphenyl-L-Alanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.