Description

(S)-Lomefloxacin Hydrochloride CAS NO 149541-59-3 is the single enantiomer form of the broad-spectrum fluoroquinolone antibiotic lomefloxacin. This optically pure form is of significant interest for advanced pharmaceutical research and development, particularly in studying stereospecific biological activity and pharmacokinetics. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in enantioselective synthesis and the development of novel antimicrobial agents.

Application

• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for quality control and analytical method development in antibiotic production.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the research-scale synthesis and process development of enantiomerically pure antibiotic formulations.
• Biochemical Research: Employed in microbiological and pharmacological studies to investigate the mechanism of action, potency, and resistance profiles of the (S)-enantiomer.
• Analytical Method Development: Essential for developing and validating chiral separation methods, such as High-Performance Liquid Chromatography (HPLC), for purity assessment.
• Preclinical Studies: Utilized in animal model research to evaluate the efficacy and toxicity profile of the specific enantiomer.

Basic Information

Product Name	(S)-Lomefloxacin Hydrochloride
CAS No.	149541-59-3
Molecular Formula	C17H19F2N3O3 • HCl
Molecular Weight	387.81 g/mol
Synonyms	(S)-Lomefloxacin HCl; (-)-Lomefloxacin Hydrochloride; (S)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride; Lomefloxacin (S)-Enantiomer Hydrochloride; (3S)-Lomefloxacin Hydrochloride; SC-47111 (S-form); Chiral Lomefloxacin HCl
EINECS	Contact for details

Quality Control

Our (S)-Lomefloxacin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets high-purity research-grade standards. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, purity, and impurities is supplied with every order to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.