Description

1-(5-Bromopyrimidin-2-yl)piperidine-4-carboxylic acid is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical candidates, particularly in kinase inhibitor research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce complex piperidine-pyrimidine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of small molecule drug candidates, especially protein kinase inhibitors.
• Chemical Biology Probes: Used in the development of tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Serves as a precursor in the design of novel active ingredients for crop protection.
• Material Science: Potential monomer or functional additive for creating specialty polymers with tailored properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process scale-up for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical space.

Basic Information

Product Name	1-(5-Bromopyrimidin-2-yl)piperidine-4-carboxylic Acid
CAS No.	149506-04-7
Molecular Formula	C10H12BrN3O2
Molecular Weight	286.13 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(5-bromo-2-pyrimidinyl)-; 1-(5-Bromo-2-pyrimidinyl)-4-piperidinecarboxylic acid; 1-(5-Bromopyrimidin-2-yl)piperidine-4-carboxylic acid; 5-Bromo-2-(4-carboxypiperidin-1-yl)pyrimidine; 149506-04-7; 1-(5-Bromopyrimidin-2-yl)piperidine-4-carboxylic acid CAS 149506-04-7
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyrimidin-2-yl)piperidine-4-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.