Description

H-Leu-Ala-Leu-Lys(Boc)-Oh is a protected tetrapeptide sequence featuring a tert-butyloxycarbonyl (Boc)-protected lysine residue. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide-based drug discovery, vaccine development, and biochemical research.

Application

• Peptide Synthesis Intermediate: A key protected fragment for the chemical synthesis of longer, biologically active peptide sequences.
• Pharmaceutical Research: Used in the development and scale-up of novel therapeutic peptides targeting various diseases.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides used in diagnostic assays and imaging studies.
• Biochemical Tool Development: Employed to study enzyme-substrate interactions, protein folding, and structure-activity relationships (SAR).
• Antigen Synthesis: Used in the production of peptide antigens for antibody generation and immunological studies.

Basic Information

Product Name	H-Leu-Ala-Leu-Lys(Boc)-Oh
CAS No.	149440-52-8
Molecular Formula	C26H49N5O7
Molecular Weight	543.70 g/mol
Synonyms	H-Leu-Ala-Leu-Lys(Boc)-OH; L-Leucyl-L-alanyl-L-leucyl-N6-[(1,1-dimethylethoxy)carbonyl]-L-lysine; Boc-Lys(Boc)-Leu-Ala-Leu-OH (sequence check); Tetrapeptide Leu-Ala-Leu-Lys(Boc); N-[(1,1-Dimethylethoxy)carbonyl]-L-lysyl-L-leucyl-L-alanyl-L-leucine; Protected Leu-Ala-Leu-Lys peptide; SPPS Building Block 149440-52-8
EINECS	Contact for details

Quality Control

Our peptide building blocks are manufactured under strict quality management systems. Each batch of H-Leu-Ala-Leu-Lys(Boc)-Oh is subjected to rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.