Description

5-Bromo-4-(4-Methylphenyl)Pyrimidine is a high-purity brominated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral agent development.
• Agrochemical Research: Used as a core structure for developing new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis & Scale-up: A critical starting material for contract research organizations (CROs) and CDMOs for custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	5-Bromo-4-(4-Methylphenyl)Pyrimidine
CAS No.	149323-50-2
Molecular Formula	C11H9BrN2
Molecular Weight	249.11 g/mol
Synonyms	5-Bromo-4-(p-tolyl)pyrimidine; 4-(4-Methylphenyl)-5-bromopyrimidine; 5-Bromo-4-(4-methylphenyl)pyrimidine; 5-Bromo-4-p-tolylpyrimidine; 149323-50-2; 4-(p-Tolyl)-5-bromopyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-(4-Methylphenyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.