Description

Adenoregulin CAS NO 149260-68-4 is a synthetic peptide analog of a natural compound found in the skin of certain frogs, known for its potent interaction with adenosine receptors. This interaction makes it a valuable research tool for studying neurological signaling pathways and receptor function. It is primarily utilized by pharmaceutical researchers and academic institutions in the fields of neuroscience, drug discovery, and biochemical assay development.

Application

• Neuroscience Research: Used as a selective ligand to study the structure and function of adenosine A1 and A2A receptors in the central nervous system.
• Drug Discovery Screening: Serves as a reference compound or positive control in high-throughput screening assays to identify novel adenosine receptor modulators.
• Biochemical Mechanism Studies: Employed to investigate adenosine-mediated signaling cascades, including their role in neuroprotection, inflammation, and sleep regulation.
• Academic & Institutional Research: A key reagent for universities and research institutes conducting fundamental studies on G-protein coupled receptors (GPCRs).
• Pharmacological Profiling: Used to characterize the binding affinity and efficacy of new chemical entities targeting adenosine receptors.
• Biomedical Assay Development: Integral in the development and validation of new in vitro assay protocols for receptor-ligand interaction studies.

Basic Information

Product Name	Adenoregulin
CAS No.	149260-68-4
Molecular Formula	C54H85N19O13S
Molecular Weight	1184.43 g/mol
Synonyms	Adenoregulin; Dmt1-δ(Z)Ado; Adenosine Regulator Peptide; Dmt-D-Arg-Phe-Lys-NH2 (adenoregulin derivative); 3-(2,6-Dimethyl-4-pyridinyl)-1-[[1-(1-oxo-3-phenylpropyl)-L-prolyl]-L-alanyl]-L-proline; PNU-101387; G Protein-Coupled Receptor Research Peptide; Adenosine A1 Receptor Ligand
EINECS	Contact for details

Quality Control

Our Adenoregulin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to ISO 9001 standards, and our quality systems are designed to support research requiring reliable and traceable biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Solubility	Soluble in DMSO, slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.