Description

L-Valine, 3-Mercapto-, Methyl Ester (9Ci) CAS NO 149207-23-8 is a specialized, sulfur-containing amino acid derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both a thiol group and a methyl ester, makes it a valuable precursor for constructing complex molecules with high stereochemical control. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients, peptide mimetics, and functionalized materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, especially protease inhibitors and other biologically active peptides.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for activity.
• Peptide Chemistry: Serves as a protected or modified amino acid residue in solid-phase and solution-phase peptide synthesis.
• Bioconjugation & Linker Chemistry: The reactive thiol group enables site-specific conjugation for creating antibody-drug conjugates (ADCs) or functionalized polymers.
• Flavor & Fragrance Precursor: Potential intermediate for synthesizing sulfur-containing flavor compounds.
• Chemical Biology Probes: Useful for creating labeled or tagged molecules to study biological pathways and protein interactions.

Basic Information

Product Name	L-Valine, 3-Mercapto-, Methyl Ester (9Ci)
CAS No.	149207-23-8
Molecular Formula	C6H13NO2S
Molecular Weight	163.24 g/mol
Synonyms	L-3-Mercaptovaline Methyl Ester; Methyl (2S)-2-amino-3-mercapto-3-methylbutanoate; (S)-Methyl 2-amino-3-mercapto-3-methylbutanoate; 3-Mercapto-L-valine methyl ester; Methyl 3-mercapto-L-valinate; L-Valine, 3-mercapto-, methyl ester; 3-Thia-L-valine methyl ester
EINECS	Contact for details

Quality Control

Our production of L-Valine, 3-Mercapto-, Methyl Ester adheres to stringent quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation of the thiol group and ensure long-term stability. The material is moisture-sensitive; keep the container tightly sealed in a cool, dry place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.