Description

Amyloid Precursor-Like Protein CAS NO 149200-34-0 is a synthetic peptide fragment derived from the amyloid precursor-like protein (APLP) family, which is structurally related to the amyloid precursor protein (APP). This high-purity biochemical is a critical research tool for investigating protein-protein interactions, neuronal development, and the molecular pathways associated with neurodegenerative diseases. It is essential for pharmaceutical R&D, academic research, and diagnostic development laboratories focused on Alzheimer's disease and related dementias.

Application

• Biochemical Research: Used as a standard or substrate in studies of APP/APLP processing, secretase enzyme activity, and amyloid-beta peptide generation.
• Neuroscience Studies: Critical for investigating the physiological and pathological roles of amyloid precursor-like proteins in neuronal signaling, adhesion, and synaptogenesis.
• Drug Discovery & Screening: Serves as a target molecule in high-throughput screening (HTS) assays to identify potential therapeutic compounds that modulate APLP function or cleavage.
• Antibody Production & Characterization: Acts as an immunogen for generating specific antibodies or as an antigen for ELISA development and antibody validation.
• Diagnostic Development: Utilized in the research and development of diagnostic assays for biomarkers related to neurodegenerative conditions.
• Cell Culture & In Vitro Models: Applied in cell-based assays to study the effects of APLP fragments on cell viability, differentiation, and signaling pathways.

Basic Information

Product Name	Amyloid Precursor-Like Protein
CAS No.	149200-34-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	APLP Fragment; Amyloid Precursor-Like Protein 1/2 Fragment; APLP1/2 Peptide; Synthetic APLP Peptide; CAS 149200-34-0; Amyloid Protein Precursor-Like Protein; APP-like Protein Fragment
EINECS	Contact for details

Quality Control

Our Amyloid Precursor-Like Protein is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or appropriate aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.