Description

Procollagen Type I (212-216) CAS NO 149128-48-3 is a specific, high-purity peptide fragment derived from the N-propeptide region of Type I procollagen. This compound is a critical research tool for studying collagen biosynthesis, processing, and related metabolic disorders. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical, and cosmetic industries for biochemical assays, biomarker development, and as a reference standard.

Application

• Biochemical Research: Used as a specific substrate or inhibitor in enzymatic assays to study procollagen N-proteinase activity.
• Biomarker Development: Serves as a key antigen for developing immunoassays (ELISA) to measure collagen synthesis and degradation markers in biological fluids.
• Cell Culture Studies: Applied in in vitro models to investigate the regulation of collagen production and extracellular matrix formation.
• Pharmaceutical R&D: Utilized in drug discovery programs targeting fibrotic diseases, bone disorders, and wound healing processes.
• Cosmetic Science: Acts as a reference standard for evaluating the efficacy of anti-aging compounds designed to stimulate collagen synthesis.
• Quality Control: Employed as a certified reference material (CRM) for the calibration and validation of analytical methods in QC laboratories.

Basic Information

Product Name	Procollagen Type I (212-216)
CAS No.	149128-48-3
Molecular Formula	C24H40N8O9
Molecular Weight	584.63 g/mol
Synonyms	Procollagen I N-Propeptide (212-216); Collagen α-1(I) Chain Fragment (212-216); PNP Peptide; (Gly-Pro-Hyp-Gly-Pro-Hyp); GPO GPO; GPH GPH; 6-Oxoprolyl-prolyl-hydroxyprolylglycylprolyl-hydroxyproline; Type I Procollagen Peptide
EINECS	Contact for details

Quality Control

Our Procollagen Type I (212-216) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry (MS) for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store the container under an inert atmosphere after opening and to allow it to reach room temperature in a desiccator before use to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0% (by weight)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.