Description

Clorazepate is a benzodiazepine derivative with significant pharmacological activity. This compound is a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) for the treatment of anxiety and seizure disorders. It is essential for pharmaceutical manufacturers and research institutions focused on developing and producing central nervous system (CNS) therapeutics. We supply high-purity Clorazepate CAS NO 149128-44-9 to support reliable and compliant global pharmaceutical supply chains.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of anxiolytic and anticonvulsant Active Pharmaceutical Ingredients (APIs).
• Research & Development: Serves as a reference standard and starting material in medicinal chemistry for developing new benzodiazepine analogs.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the controlled production of finished dosage forms under Good Manufacturing Practice (GMP) conditions.
• Analytical Testing: Employed as a high-purity standard in quality control laboratories for HPLC, GC, or spectroscopic method development and validation.
• Preclinical Studies: Utilized in pharmacological and toxicological research to study the mechanism of action and safety profiles of benzodiazepines.

Basic Information

Product Name	Clorazepate
CAS No.	149128-44-9
Molecular Formula	C16H11ClN2O3
Molecular Weight	314.72 g/mol
Synonyms	Clorazepic Acid; 7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic Acid; 7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic Acid; Clorazepate Dipotassium (Salt Form Precursor); Azene (related to salt form); Tranxene (related to salt form); 1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-
EINECS	Contact for details

Quality Control

Our Clorazepate is manufactured and tested to meet stringent quality standards suitable for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and GC. We provide full traceability and support regulatory filings. A Certificate of Analysis (COA) documenting all test results is available for every shipment to ensure compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤20 ppm
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.