Description

Clorazepate is a benzodiazepine derivative and a key pharmaceutical active ingredient. It is valued for its anxiolytic and sedative properties, making it a critical component in the formulation of central nervous system (CNS) medications. This high-purity compound is essential for pharmaceutical manufacturers and research institutions developing treatments for anxiety disorders, insomnia, and related conditions. Consistent quality and reliable supply are paramount for ensuring the efficacy and safety of the final drug products.

Application

• Primary active pharmaceutical ingredient (API) in anxiolytic and sedative drug formulations.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Key intermediate in advanced pharmaceutical research and development for CNS-targeted therapies.
• Used in clinical studies and pharmacological research to investigate benzodiazepine receptor interactions.
• Essential component for compounding pharmacies requiring specific, high-purity neuroactive compounds.

Basic Information

Item	Details
Product Name	Clorazepate
CAS No.	149128-43-8
Molecular Formula	C16H11ClN2O3
Molecular Weight	314.72 g/mol
Synonyms	Clorazepate Dipotassium; Tranxene; Azene; Clorazepic Acid; 7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic Acid; 7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic Acid Dipotassium Salt; CLZ
EINECS	Contact for details

Quality Control

Our Clorazepate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmaceutical-grade specifications, including identity, purity, and impurity profile verification. We provide a Certificate of Analysis (COA) with each shipment, detailing all test results against relevant pharmacopeial standards (e.g., USP, EP). Our commitment to cGMP compliance ensures traceability and consistency for all regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.