Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[[2-(Ethylamino)Ethyl]Amino]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs). It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the production of next-generation antimicrobial agents. Our supply ensures the stringent quality and consistency required for sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of advanced fluoroquinolone antibiotic candidates.
• Antimicrobial Research: Serves as a core scaffold for developing new compounds with activity against resistant bacterial strains.
• Chemical Synthesis: Used in organic and medicinal chemistry research for constructing complex nitrogen-containing heterocycles.
• API Development: Integral in the process development and scale-up of new Active Pharmaceutical Ingredients targeting DNA gyrase and topoisomerase IV.
• Reference Standard: Suitable for use as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[[2-(Ethylamino)Ethyl]Amino]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	149091-97-4
Molecular Formula	C₁₇H₂₁FN₄O₃
Molecular Weight	348.38 g/mol
Synonyms	1-Cyclopropyl-7-[[2-(ethylamino)ethyl]amino]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[(2-(ethylamino)ethyl)amino]-4-oxoquinoline-3-carboxylic acid; 7-[(2-(Ethylamino)ethyl)amino]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; Intermediate for Garenoxacin; Garenoxacin intermediate; DX-619 intermediate; T-3811 intermediate; 149091-97-4
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with the rigorous standards required for pharmaceutical R&D and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.