Description

Amikacin Sulfate Salt is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. This compound is critical for its potent bactericidal activity against a wide spectrum of Gram-negative and some Gram-positive bacteria, including resistant strains. It is primarily required by pharmaceutical manufacturers for the formulation of injectable antibiotic solutions used in hospital and clinical settings to treat serious systemic infections.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of sterile injectable antibiotic formulations.
• Hospital Infection Treatment: Used in drugs targeting severe infections like septicemia, meningitis, and respiratory tract infections caused by susceptible organisms.
• Veterinary Medicine: Formulated for treating bacterial infections in animals.
• Research & Development: Serves as a reference standard and key intermediate in microbiological and pharmacological research.
• Combination Therapies: Used in synergistic antibiotic combinations to combat multi-drug resistant bacterial strains.

Basic Information

Product Name	Amikacin Sulfate Salt
CAS No.	149022-22-0
Molecular Formula	C22H43N5O13 • xH2SO4
Molecular Weight	585.60 (for Amikacin base)
Synonyms	Amikacin Sulphate; Amikacin Sulfate; Amikacin Sulfate Hydrate; (+)-Amikacin Sulfate; BAY 41-6551 (sulfate salt); Amikacin (sulfate); 4-Amino-1-(1,3-dihydroxy-2-propyl)kanamycin B Sulfate; 1-N-[(S)-4-Amino-2-hydroxybutyryl]-6'-O-(3-amino-3-deoxy-α-D-glucopyranosyl)kanamycin A Sulfate
EINECS	Contact for details

Quality Control

Our Amikacin Sulfate Salt is manufactured and tested under strict quality management systems. It meets high-purity standards suitable for pharmaceutical applications, with specifications aligned with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, potency, and related substances is provided with each batch to ensure traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC, on anhydrous basis)	95.0% - 102.0%
pH (1% solution)	5.5 - 7.5
Water Content (KF)	≤ 10.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Bacterial Endotoxins	< 1.0 EU/mg (as per application grade)
Sterility (for sterile grade)	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.