Description

Monomethylarginine Di-(4-Hydroxyazobenzene-4'-Sulfonate) is a specialized biochemical reagent primarily used as a potent and selective inhibitor of nitric oxide synthase (NOS) isoforms. This compound matters for researchers and developers as it provides a critical tool for studying the complex role of nitric oxide signaling in physiological and pathological processes. It is essential for pharmaceutical R&D, academic research in biochemistry and cell biology, and the development of therapeutic agents targeting cardiovascular, neurological, and inflammatory diseases.

Application

• Nitric Oxide Synthase (NOS) Inhibition Studies: Used as a key research tool to selectively inhibit NOS activity in enzymatic assays and cellular models.
• Pharmaceutical Research & Development: Serves as a reference standard and lead compound in the discovery of drugs targeting conditions like sepsis, stroke, and neurodegeneration.
• Biochemical Pathway Analysis: Employed to elucidate the role of nitric oxide in signal transduction, immune response, and vascular regulation.
• Cell Culture & In Vitro Diagnostics: Applied in controlled experiments to understand the effects of modulated NO production on cell viability and function.
• Neuroscience Research: Utilized to investigate the impact of NOS inhibition on neuronal signaling and related neurological disorders.
• Reference Standard Manufacturing: Supplied as a high-purity compound for quality control and calibration in analytical laboratories.

Basic Information

Item	Detail
Product Name	Monomethylarginine Di-(4-Hydroxyazobenzene-4'-Sulfonate)
CAS No.	149017-67-4
Molecular Formula	C26H28N8O10S2
Molecular Weight	668.68 g/mol
Synonyms	L-NG-Monomethylarginine Di-(4-Hydroxyazobenzene-4'-Sulfonate); Nω-Monomethyl-L-arginine Di(p-hydroxyazobenzenesulfonate); L-NMMA Di-(pHABS); Nitric Oxide Synthase Inhibitor I; NOS Inhibitor; 2-Amino-5-[(methylamino)pentanoic acid] compound with 4-[(4-hydroxyphenyl)diazenyl]benzenesulfonic acid (2:1); UNII-8Z3407PUS1
EINECS	Contact for details

Quality Control

Our Monomethylarginine Di-(4-Hydroxyazobenzene-4'-Sulfonate) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR). A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.