Description

4-Aminobenzotrifluoride Hydrobromide is a high-purity organic salt derivative of 4-aminobenzotrifluoride, serving as a critical building block in advanced chemical synthesis. Its value lies in the combination of the electron-withdrawing trifluoromethyl group and the reactive amino functionality, which is stabilized as a hydrobromide salt for improved handling and shelf-life. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients, particularly in the creation of fluorinated compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group improves lipophilicity and biological efficacy.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Industry: Acts as an intermediate for producing fluorinated dyes and pigments with unique color fastness and optical properties.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to introduce anilino groups into complex molecular architectures.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on organofluorine chemistry and novel synthetic methodologies.

Basic Information

Product Name	4-Aminobenzotrifluoride Hydrobromide
CAS No.	148819-81-2
Molecular Formula	C7H7F3N·HBr
Molecular Weight	246.05 g/mol
Synonyms	4-(Trifluoromethyl)aniline Hydrobromide; α,α,α-Trifluoro-p-toluidine Hydrobromide; p-Aminobenzotrifluoride Hydrobromide; 4-Amino-α,α,α-trifluorotoluene Hydrobromide; 4-(Aminomethyl)benzotrifluoride Hydrobromide (common misnomer); 4-TFMA·HBr; 4-CF3C6H4NH2·HBr
EINECS	Contact for details

Quality Control

Our 4-Aminobenzotrifluoride Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.