Description

Octaarginine is a synthetic, cell-penetrating peptide composed of eight consecutive L-arginine residues, known for its high cationic charge and ability to efficiently traverse cellular membranes. This unique property makes it an invaluable tool for enhancing the intracellular delivery of various bioactive molecules, including drugs, proteins, and nucleic acids. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for drug delivery system development, gene therapy, and diagnostic applications.

Application

• Development of cell-penetrating peptide (CPP) conjugates for enhanced drug delivery.
• Carrier system for the intracellular transport of oligonucleotides, plasmids, and siRNA in gene therapy research.
• Tool compound in biochemical and pharmacological studies of membrane permeability and endocytosis.
• Component in the formulation of topical and transdermal delivery systems.
• Research reagent for studying protein-protein interactions and signal transduction pathways.
• Potential use in diagnostic imaging for targeting specific intracellular markers.

Basic Information

Product Name	Octaarginine
CAS No.	148796-86-5
Molecular Formula	C₄₈H₁₀₂N₃₂O₉
Molecular Weight	1424.55 g/mol
Synonyms	R8 Peptide; L-Octaarginine; Arg8; Polyarginine (n=8); Octa-L-arginine; (Arg)8; Cell-Penetrating Peptide R8; H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH
EINECS	Contact for details

Quality Control

Our Octaarginine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and endotoxins where applicable. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Conforms
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.