Description

Glycoprotein B, Human Herpesvirus-6 is a key viral envelope protein essential for host cell entry and membrane fusion. This highly purified antigen is critical for advancing research into HHV-6 pathogenesis and developing diagnostic assays and therapeutic strategies. It is primarily utilized by researchers and manufacturers in the fields of virology, immunology, and infectious disease diagnostics. The product is supplied with a Certificate of Analysis and is identified by CAS No. 148770-71-2.

Application

• Immunoassay Development: As a critical antigen for the development and calibration of ELISA and other serological tests for HHV-6 antibody detection.
• Vaccine Research: Serving as a target antigen in preclinical studies for vaccine candidates against Human Herpesvirus-6.
• Antibody Production & Purification: Used for immunizing animals to generate polyclonal or monoclonal antibodies specific to HHV-6 glycoprotein B.
• Cellular & Molecular Biology Studies: Investigating virus-host interactions, viral entry mechanisms, and neutralizing antibody responses.
• Diagnostic Kit Manufacturing: A core component in the production of commercial diagnostic kits for clinical and research laboratories.
• Quality Control Reference Standard: Acting as a positive control or reference material in assay validation and quality control protocols.

Basic Information

Product Name	Glycoprotein B, Human Herpesvirus-6
CAS No.	148770-71-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HHV-6 Glycoprotein B; HHV-6 gB; gpB, HHV-6; HHV-6 Envelope Glycoprotein B; Human Herpesvirus 6 Glycoprotein B; HHV-6 Major Envelope Glycoprotein; HHV-6 Viral Antigen
EINECS	Contact for details

Quality Control

Our Glycoprotein B, Human Herpesvirus-6 is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation, and functional activity evaluation. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your research and development quality systems.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solution
Identification (SDS-PAGE/Western Blot)	Consistent with HHV-6 Glycoprotein B
Purity (SDS-PAGE)	>90%
Protein Content	Determined by UV absorbance or BCA assay
Endotoxin Level	<1.0 EU/µg (for in vitro use)
Biological Activity	Confirmed by ELISA or cell-based assay
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.