Description

1,1,2,2-Tetrafluoro-2-(1,1,2,2-Tetrafluoro-2-Iodoethoxy)-Ethanesulfonamide is a specialized fluorinated organic intermediate featuring a unique combination of perfluoroether, sulfonamide, and iodoalkyl functional groups. This compound is valued for its role as a key building block in the synthesis of advanced materials and pharmaceuticals, where its fluorine content imparts desirable properties such as chemical inertness, thermal stability, and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and antiviral therapies.
• Agrochemical Synthesis: Used in developing next-generation fluorinated pesticides and herbicides, where the fluorine atoms enhance biological activity, metabolic stability, and environmental persistence.
• Fluorinated Polymer & Surfactant Production: Acts as a monomer or modifier for creating high-performance polymers, coatings, and surfactants with exceptional oil, water, and stain resistance.
• Material Science Research: Employed in academic and industrial R&D for exploring new fluorinated compounds with specific electronic or surface properties.
• Liquid Crystal & Electronic Chemicals: Potential use in the synthesis of fluorinated components for liquid crystal displays (LCDs) and dielectric materials.
• Radiolabeling & Tracer Studies: The iodine atom presents opportunities for radiolabeling (e.g., with I-125) for use in medical imaging or metabolic pathway tracing research.

Basic Information

Product Name	1,1,2,2-Tetrafluoro-2-(1,1,2,2-Tetrafluoro-2-Iodoethoxy)-Ethanesulfonamide
CAS No.	148716-83-0
Molecular Formula	C4H2F8INO3S
Molecular Weight	438.99 g/mol
Synonyms	1,1,2,2-Tetrafluoro-2-(1,1,2,2-tetrafluoro-2-iodoethoxy)ethanesulfonamide; 2-(1,1,2,2-Tetrafluoro-2-iodoethoxy)-1,1,2,2-tetrafluoroethanesulfonamide; Tetrafluoro(1,1,2,2-tetrafluoro-2-iodoethoxy)ethanesulfonamide; 1,1,2,2-Tetrafluoro-2-(2-iodo-1,1,2,2-tetrafluoroethoxy)ethanesulfonic acid amide; Ethanesulfonamide, 1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoro-2-iodoethoxy)-; Perfluoro(2-iodoethoxy)ethanesulfonamide (common name); Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our 1,1,2,2-Tetrafluoro-2-(1,1,2,2-Tetrafluoro-2-Iodoethoxy)-Ethanesulfonamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR (¹H, ¹⁹F, ¹³C) for structural confirmation, and GC-MS for impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be amber-colored or kept in opaque secondary packaging. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.