Description

Preprotachykinin B (50-79) is a defined peptide fragment derived from the preprotachykinin B precursor protein. This compound is of significant interest in biochemical and pharmacological research for its role in studying neurokinin signaling pathways and receptor interactions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuroscience, peptide chemistry, and drug discovery programs.

Application

• Neuroscientific Research: Used as a reference standard and tool compound for investigating the function and distribution of Neurokinin B (NKB) and related tachykinin peptides.
• Receptor Binding Studies: Employed in in vitro assays to characterize binding affinities and selectivity profiles for neurokinin receptors (NK1, NK2, NK3).
• Biochemical Pathway Analysis: Serves as a substrate or intermediate in studies focused on peptide processing, post-translational modifications, and precursor protein biology.
• Pharmaceutical Development: Acts as a starting material or analytical standard in the development and quality control of peptide-based therapeutics targeting neurological and inflammatory conditions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in neuroendocrinology, pain signaling, and reproductive physiology.

Basic Information

Product Name	Preprotachykinin B (50-79)
CAS No.	148597-04-0
Molecular Formula	C152H246N46O41S
Molecular Weight	~3399.9 g/mol
Synonyms	Neurokinin B (50-79); hNKB(50-79); Preprotachykinin B Fragment 50-79; Tachykinin Precursor 2 (50-79); TAC3 (50-79); NKB Precursor Fragment; Neurokinin B Precursor Peptide; PPBT (50-79)
EINECS	Contact for details

Quality Control

Our Preprotachykinin B (50-79) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by comprehensive analytical data. Certificates of Analysis (COA) detailing purity, identity, and peptide content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.