Description

Fmoc-(Fmochmb)Val-Oh CAS NO 148515-86-0 is a specialized, orthogonally protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound matters for its critical role in enabling the synthesis of complex peptides and peptidomimetics, particularly those requiring selective deprotection strategies. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel therapeutic peptides, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for the controlled, sequential assembly of peptides, especially in Fmoc-based strategies.
• Peptidomimetic Research: For the design and synthesis of peptide analogs with enhanced stability, bioavailability, or biological activity.
• Pharmaceutical Intermediate: In the production of active pharmaceutical ingredients (APIs) for peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation and Probe Development: For creating labeled peptides used in biochemical assays, imaging, and diagnostic applications.
• Combinatorial Chemistry Libraries: As a valuable component for generating diverse peptide libraries for high-throughput screening in drug discovery.
• Academic and Industrial R&D: For fundamental research in peptide science, protein engineering, and chemical biology.

Basic Information

Product Name	Fmoc-(Fmochmb)Val-Oh
CAS No.	148515-86-0
Molecular Formula	C31H31NO6
Molecular Weight	513.58 g/mol
Synonyms	Fmoc-Val(Fmochmb)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyloxy]-L-valine; Fmoc-N-(Fmoc-hydroxy-4-methylbenzyl)-L-valine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl][[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]amino]-3-methylbutanoic acid; Fmoc-Val(Fmoc-Hmb)-OH; Fmoc-(Fmoc-Hmb)Val-OH; Nα-Fmoc-Nβ-(Fmoc-hydroxy-4-methylbenzyl)-L-valine; Fmoc-Val(Fmoc-Hmb)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-(Fmochmb)Val-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.