Description

Fmoc-(Fmochmb)Ala-Oh is a specialized, orthogonally protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound matters for its critical role in enabling the synthesis of complex peptides and peptidomimetics, particularly where selective deprotection strategies are required. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for the controlled assembly of peptide chains, especially in Fmoc/tBu strategies.
• Pharmaceutical Research: For the development and production of peptide-based drug candidates, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation: Used to introduce specific, protected functional handles into biomolecules for subsequent labeling or cross-linking.
• Combinatorial Chemistry: A valuable reagent in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial R&D: Fundamental research in peptide chemistry, protein engineering, and molecular biology.
• Production of Custom Peptides: Serves as a critical intermediate for CROs and CDMOs offering bespoke peptide synthesis services.

Basic Information

Product Name	Fmoc-(Fmochmb)Ala-Oh
CAS No.	148515-85-9
Molecular Formula	C30H29NO6
Molecular Weight	499.56 g/mol
Synonyms	Fmoc-(Fmochmb)Ala-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-3-oxopropyl]-L-alanine; Fmoc-Ala(Fmochmb)-OH; Nα-Fmoc-Nβ-(Fmochmb)-L-diaminopropionic Acid; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-3-oxopropyl]propanoic acid; Fmoc-Dap(Fmochmb)-OH; L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-3-oxopropyl]-
EINECS	Contact for details

Quality Control

Our Fmoc-(Fmochmb)Ala-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for sensitive peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance and supply chain traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to maintain stability and purity. Allow the sealed container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.