Description

Glycoprotein 35, Hepatitis C Virus is a recombinant viral envelope glycoprotein derived from the Hepatitis C Virus (HCV). This high-purity protein is a critical reagent for virology research, vaccine development, and diagnostic assay manufacturing. It is essential for researchers and developers in the pharmaceutical, biotechnology, and in-vitro diagnostics industries working on HCV therapeutics, immunogenicity studies, and serological test development.

Application

• Diagnostic Assay Development: Used as a key antigen in the development and calibration of ELISA, immunoblot, and rapid test kits for the detection of HCV antibodies.
• Vaccine Research: Serves as a target antigen for evaluating vaccine immunogenicity and eliciting neutralizing antibodies in preclinical studies.
• Antiviral Drug Screening: Employed in high-throughput screening (HTS) platforms and binding assays to identify and characterize novel antiviral compounds targeting HCV entry.
• Immunological Studies: Utilized for studying host immune response, epitope mapping, and understanding virus-host interactions.
• Reference Standard: Acts as a purified reference standard for quality control and lot-to-lot consistency testing of other HCV-related reagents and diagnostics.
• Academic & Contract Research: Fundamental tool for basic virology research in academic institutions and contract research organizations (CROs).

Basic Information

Item	Details
Product Name	Glycoprotein 35, Hepatitis C Virus
CAS No.	148349-77-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HCV Glycoprotein 35; HCV Envelope Glycoprotein; HCV E2 Glycoprotein; Hepatitis C Virus Glycoprotein E2; Recombinant HCV gp35; HCV Antigen; Viral Envelope Protein HCV
EINECS	Contact for details

Quality Control

Our Glycoprotein 35, Hepatitis C Virus is produced under stringent conditions and undergoes comprehensive analytical testing to ensure high purity, specificity, and biological activity. Each batch is characterized using techniques including SDS-PAGE, Western Blot, and HPLC to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (Western Blot)	Reacts with anti-HCV antibodies
Purity (SDS-PAGE)	> 90%
Protein Content (BCA)	> 95% of total weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (ELISA)	Binding to specific monoclonal antibodies confirmed
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.