Description

4-Chloro-2-(Methylthio)Pyrimidine-5-Carboxaldehyde is a versatile and high-value pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and methylthio substituents adjacent to a reactive aldehyde group, makes it an essential precursor for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its pyrimidine core.
• Material Science Research: Serves as a precursor for the development of functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and biochemical tools due to its reactive aldehyde functionality for conjugation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-2-(Methylthio)Pyrimidine-5-Carboxaldehyde
CAS No.	148256-82-0
Molecular Formula	C6H5ClN2OS
Molecular Weight	188.63 g/mol
Synonyms	4-Chloro-2-(methylsulfanyl)pyrimidine-5-carbaldehyde; 5-Formyl-4-chloro-2-methylthiopyrimidine; 4-Chloro-2-methylthio-5-pyrimidinecarboxaldehyde; 2-Methylthio-4-chloro-5-pyrimidinecarboxaldehyde; 4-Chloro-2-methylmercaptopyrimidine-5-carboxaldehyde; 4-Chloro-2-(methylthio)-5-pyrimidinecarboxaldehyde; 4-Chloro-2-(methylsulfanyl)-5-pyrimidinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Methylthio)Pyrimidine-5-Carboxaldehyde is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize repeated exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.