Description

Subtilisin Inhibitor P20, Rice Bran is a specific, naturally derived protease inhibitor. This compound is critical for controlling unwanted proteolytic activity in research and industrial processes, ensuring product stability and process integrity. It is primarily utilized by the biotechnology, pharmaceutical, and diagnostic industries for applications requiring precise enzyme inhibition. Its origin from rice bran offers a natural and biocompatible profile for sensitive applications.

Application

• Biopharmaceutical Manufacturing: Used to inhibit subtilisin and related serine proteases during the purification and formulation of therapeutic proteins and peptides, preventing degradation.
• Diagnostic Reagent Formulation: Serves as a stabilizing agent in enzyme-based diagnostic kits to prevent protease-mediated breakdown of key components, ensuring assay reliability.
• Biochemical & Life Science Research: An essential tool for studying protease function, enzyme kinetics, and signal transduction pathways in cell biology and biochemistry laboratories.
• Cell Culture & Tissue Engineering: Employed to protect sensitive cells, growth factors, and extracellular matrix components from proteolytic damage in vitro.
• Food & Beverage Enzyme Control: Potential application in controlling endogenous or added protease activity during processing to improve texture, flavor, or shelf-life of products.
• Cosmetic Formulations: Can be used to stabilize protein-based active ingredients (e.g., growth factors, peptides) in skincare products against enzymatic degradation.

Basic Information

Product Name	Subtilisin Inhibitor P20, Rice Bran
CAS No.	148197-65-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Rice Bran Trypsin/Subtilisin Inhibitor; Subtilisin Inhibitor from Rice Bran; RBTI; Protease Inhibitor P20; Oryza sativa Trypsin/Subtilisin Inhibitor; Serine Protease Inhibitor (Rice); Bowman-Birk Type Inhibitor (Rice); Trypsin/Subtilisin Inhibitor RBTI
EINECS	Contact for details

Quality Control

Our Subtilisin Inhibitor P20, Rice Bran is produced and tested under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and functional activity. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications for assay, purity, and biological activity. We support compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Protein Content (Biuret)	≥ 90.0%
Inhibitory Activity (vs. Subtilisin)	≥ 10,000 U/mg
Moisture Content (KF)	≤ 5.0%
Residue on Ignition	≤ 2.0%
Biological Safety (Endotoxin)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.