Description

Pyrazolo[1,5-A]Pyrido[3,4-E]Pyrimidin-6(7H)-One is a high-purity, advanced pharmaceutical intermediate belonging to a class of fused heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of targeted small-molecule therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of investigational new drugs (INDs) and novel APIs.
• Oncology Research: Used in the development of kinase inhibitors and other targeted cancer therapeutics due to its privileged scaffold.
• Antiviral Drug Development: Serves as a core structure for compounds being researched against various viral pathogens.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag to study enzyme function and protein interactions.
• Academic & Institutional R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Contract Manufacturing: Supplied to CDMOs for scale-up and cGMP production of clinical trial materials.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrido[3,4-E]Pyrimidin-6(7H)-One
CAS No.	148191-54-2
Molecular Formula	C9H6N4O
Molecular Weight	186.17 g/mol
Synonyms	7H-Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-one; Pyrazolopyridopyrimidinone; 148191-54-2; 6H-Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-one; Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6(7H)-one; 7H-Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-one (9CI); SCHEMBL2354541; BCP31821
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyrido[3,4-E]Pyrimidin-6(7H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.