Description

Ethyl 7-[(E)-2-(Dimethylamino)Vinyl]Pyrazolo-[1,5-A]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazolopyrimidine core structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the development of novel therapeutic agents.

Application

• Critical intermediate in the synthesis of kinase inhibitor candidates for oncology research.
• Key building block for the development of pharmaceutical compounds targeting inflammatory and autoimmune diseases.
• Used in medicinal chemistry research for structure-activity relationship (SAR) studies and lead optimization.
• Precursor in the production of specialized fine chemicals and complex heterocyclic molecules.
• Employed in custom synthesis and contract manufacturing for preclinical and clinical-stage drug development.

Basic Information

Product Name	Ethyl 7-[(E)-2-(Dimethylamino)Vinyl]Pyrazolo-[1,5-A]Pyrimidine-6-Carboxylate
CAS No.	148191-33-7
Molecular Formula	C₁₃H₁₆N₄O₂
Molecular Weight	260.29 g/mol
Synonyms	Ethyl 7-[(E)-2-(dimethylamino)ethenyl]pyrazolo[1,5-a]pyrimidine-6-carboxylate; 7-[(E)-2-(Dimethylamino)vinyl]pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; Ethyl 7-(2-(dimethylamino)vinyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate; Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-[(E)-2-(dimethylamino)ethenyl]-, ethyl ester; CAS 148191-33-7
EINECS	Contact for details

Quality Control

Our production of Ethyl 7-[(E)-2-(Dimethylamino)Vinyl]Pyrazolo-[1,5-A]Pyrimidine-6-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured in a GMP-compliant environment, and each lot undergoes comprehensive analytical testing. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.