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tert-Butyloxycarbonyl-Phenylalanyl-Leucyl-Phenylalanyl-Leucyl-Phenylalanyl-Oh CAS NO 148182-34-7


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CAS No.:148182-34-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyloxycarbonyl-Phenylalanyl-Leucyl-Phenylalanyl-Leucyl-Phenylalanyl-Oh is a synthetic, protected hexapeptide sequence featuring a C-terminal acid and the tert-butyloxycarbonyl (Boc) protecting group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of complex peptide chains. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and contract research organizations (CROs) for the development of therapeutic peptides and biochemical research tools.

Application

  • Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled, sequential assembly of longer bioactive peptide sequences.
  • Pharmaceutical Research & Development: For the discovery and development of novel peptide-based therapeutics targeting various diseases.
  • Biochemical Research: As a substrate or inhibitor in enzymatic studies and structure-activity relationship (SAR) investigations.
  • Custom Peptide Manufacturing: Serves as a premium-grade starting material for the production of custom peptides under GMP or non-GMP conditions.
  • Proteomics and Peptidomics: Used in the synthesis of reference standards and labeled peptides for analytical method development.
  • Academic Research: A valuable reagent for university laboratories studying peptide chemistry, folding, and function.

Basic Information

Product Name tert-Butyloxycarbonyl-Phenylalanyl-Leucyl-Phenylalanyl-Leucyl-Phenylalanyl-Oh
CAS No. 148182-34-7
Molecular Formula C48H66N6O9
Molecular Weight 871.1 g/mol
Synonyms Boc-Phe-Leu-Phe-Leu-Phe-OH; Boc-Phe-Leu-Phe-Leu-Phe; Boc-F-L-F-L-F-OH; tert-Butoxycarbonyl-Phenylalanyl-Leucyl-Phenylalanyl-Leucyl-Phenylalanine; N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-leucyl-L-phenylalanine; Hexapeptide Boc-Phe-Leu-Phe-Leu-Phe-OH; Protected Peptide Fragment 148182-34-7
EINECS Contact for details

Quality Control

Our peptide building blocks are produced under stringent quality protocols to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical characterization, including HPLC, MS, and NMR, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support research and development needs with materials suitable for laboratory use and can discuss GMP-grade manufacturing for advanced clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95.0%
Assay ≥ 97.0% (on anhydrous basis)
Water Content (KF) ≤ 3.0%
Single Impurity (HPLC) ≤ 1.0%
Optical Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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