Description

Defensin HNP-1 (human) CAS NO 148093-65-6 is a human neutrophil peptide-1, a key member of the α-defensin family of antimicrobial peptides. This compound plays a critical role in the innate immune response, offering broad-spectrum activity against bacteria, fungi, and certain viruses. It is essential for research and development in the pharmaceutical, biotechnology, and life science sectors, particularly for studies in immunology, antimicrobial drug discovery, and novel therapeutic formulations.

Application

• Biomedical Research: Fundamental studies on innate immunity, host defense mechanisms, and peptide biology.
• Antimicrobial Agent Development: Serves as a lead compound or model for designing novel anti-infective therapeutics and peptide-based antibiotics.
• Drug Delivery Systems: Investigation into conjugates or formulations that utilize defensin's properties for targeted delivery.
• Diagnostic Reagent Component: Used in the development of assays and kits for detecting immune response markers or microbial presence.
• Cosmeceutical & Skincare Research: Exploration of its anti-inflammatory and antimicrobial properties for advanced skincare product development.
• Veterinary Medicine: Research into applications for animal health and antimicrobial treatments in livestock.

Basic Information

Product Name	Defensin HNP-1 (human)
CAS No.	148093-65-6
Molecular Formula	C95H141N39O24S5
Molecular Weight	~ 2280.6 g/mol
Synonyms	Human Neutrophil Peptide-1; HNP-1; Defensin, alpha 1; DEFA1; NP-1; HP-1; MRS (Microbicidal/Pore-Forming Peptide); α-Defensin 1
EINECS	Contact for details

Quality Control

Our Defensin HNP-1 (human) is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and biological activity. Certificates of Analysis (COA) detailing purity (by HPLC), molecular weight confirmation (by MS), and endotoxin levels are provided. We adhere to high-purity peptide standards suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Molecular Weight (MS)	2280.6 ± 2 Da
Water Content (KF)	≤ 5.0 %
Endotoxin Level (LAL)	< 10 EU/mg
Biological Activity	Assay-dependent; Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.