Description

n-(5-Thioxo-L-Prolyl)-L-Cysteine is a specialized synthetic peptide derivative that combines proline and cysteine moieties, featuring a unique thioxo modification. This compound is valued for its role as a key intermediate and building block in advanced pharmaceutical research and peptide synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
• Peptide Synthesis: An essential reagent in solid-phase and solution-phase peptide synthesis for constructing complex peptide sequences.
• Protease Inhibitor Development: Explored in the design and development of protease inhibitors due to its modified cysteine structure.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Cosmeceutical Applications: Investigated for potential use in advanced skincare formulations targeting antioxidant and anti-aging properties.

Basic Information

Product Name	n-(5-Thioxo-L-Prolyl)-L-Cysteine
CAS No.	148076-52-2
Molecular Formula	C8H12N2O3S2
Molecular Weight	248.32 g/mol
Synonyms	L-Cysteine, N-(5-thioxo-L-prolyl)-; (2R)-2-[[(2S)-5-Thioxopyrrolidine-2-carbonyl]amino]-3-sulfanylpropanoic Acid; N-[(5-Thioxo-L-prolyl)]-L-cysteine; TP-Cysteine; Thioxoprolyl-Cysteine; NSC 339587; 148076-52-2; 5-Thioxoprolyl-Cysteine
EINECS	Contact for details

Quality Control

Our n-(5-Thioxo-L-Prolyl)-L-Cysteine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with complete traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and ensure long-term stability. The material is easily oxidized and should be handled in a controlled environment to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.