Description

N,9-o-Diacetylneuraminic Acid Ammonium is a high-purity ammonium salt derivative of a key sialic acid, offering enhanced stability and solubility for advanced biochemical applications. This compound serves as a critical intermediate and reference standard in the synthesis and analysis of complex glycoconjugates and sialylated molecules. It is essential for research and development in the pharmaceutical, biotechnology, and diagnostic sectors, where precise control over glycosylation patterns is paramount for drug efficacy and biomarker discovery.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel sialidase inhibitors, antiviral agents, and anti-inflammatory drugs targeting sialic acid-mediated pathways.
• Glycobiology Research: Serves as a crucial substrate, standard, or building block for studying sialyltransferase activity, cell surface recognition, and glycan biosynthesis.
• Diagnostic Reagent Manufacturing: Employed in the production of calibration standards and components for diagnostic kits detecting sialic acid-related diseases or infections.
• Bioconjugation & Vaccine Development: Acts as a starting material for conjugating carbohydrates to carrier proteins in the development of conjugate vaccines and targeted therapeutics.
• Nutraceutical & Cosmetic Research: Investigated for potential applications in functional foods and high-end skincare products due to its role in cellular communication and hydration.

Basic Information

Product Name	N,9-o-Diacetylneuraminic Acid Ammonium
CAS No.	148067-22-5
Molecular Formula	C13H22N2O10 • xNH3
Molecular Weight	366.33 g/mol (Free acid, C13H22N2O10)
Synonyms	5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid, 9-O-acetyl-, ammonium salt; Ammonium N,9-O-diacetylneuraminate; N,9-Di-O-acetylneuraminic acid ammonium salt; Sialic acid, N,9-di-O-acetyl-, ammonium salt; 9-O-Acetyl-N-acetylneuraminic acid ammonium salt; Neu5,9Ac2 ammonium salt
EINECS	Contact for details

Quality Control

Our N,9-o-Diacetylneuraminic Acid Ammonium is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets stringent specifications for research and cGMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.