Description

Eptifibatide Acetate is a high-purity synthetic cyclic heptapeptide, a potent and selective antagonist of the platelet glycoprotein IIb/IIIa receptor. This compound is critical for inhibiting platelet aggregation, making it a valuable active pharmaceutical ingredient (API) in the development of antithrombotic therapies. It is primarily required by pharmaceutical manufacturers and research institutions engaged in cardiovascular drug development and advanced biochemical research.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of injectable antithrombotic drugs.
• Reference Standard in analytical laboratories for quality control and method validation of eptifibatide-based products.
• Biochemical Research for studying platelet aggregation mechanisms and thrombosis pathways.
• Pharmaceutical Intermediates in the synthesis of more complex therapeutic agents targeting cardiovascular diseases.
• Clinical Trial Materials for the development of new antiplatelet therapies and generics.

Basic Information

Product Name	Eptifibatide Acetate
CAS No.	148031-34-9
Molecular Formula	C35H49N11O9S2 • xC2H4O2
Molecular Weight	831.96 g/mol (free base)
Synonyms	Integrilin (Brand Name); Eptifibatide; MK-0852; N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic (1→6)-disulfide, acetate; L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-disulfide, acetate; GP IIb/IIIa Inhibitor; Cyclo(S,S)-[Mpr-Har-Gly-Asp-Trp-Pro-Cys]-Acetate
EINECS	Contact for details

Quality Control

Our Eptifibatide Acetate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided, confirming compliance with specifications for identity, purity, and impurities. We support development with regulatory-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Acetate Content	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.