Description

4-Chloro-2-(trifluoromethyl)thieno[3,2-d]pyrimidine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a halogenated pyrimidine ring with a thiophene and a trifluoromethyl group, enabling precise modifications for creating novel compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients. Its structural features make it a critical precursor for creating molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thienopyrimidine scaffold.
• Material Science: Serves as a precursor for organic electronic materials, such as semiconductors or light-emitting components, due to its fused ring system.
• Chemical Synthesis: Employed as a versatile intermediate in academic and industrial research for constructing complex heterocyclic libraries.
• Fluorinated Compound Development: The trifluoromethyl group makes it valuable for creating compounds with enhanced metabolic stability and lipophilicity.

Basic Information

Product Name	4-Chloro-2-(trifluoromethyl)thieno[3,2-d]pyrimidine
CAS No.	147972-27-8
Molecular Formula	C7H2ClF3N2S
Molecular Weight	238.62 g/mol
Synonyms	4-Chloro-2-(trifluoromethyl)thieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine, 4-chloro-2-(trifluoromethyl)-; 4-Chloro-2-trifluoromethylthieno[3,2-d]pyrimidine; 2-(Trifluoromethyl)-4-chlorothieno[3,2-d]pyrimidine; 4-Chloro-2-(trifluoromethyl)-thieno[3,2-d]pyrimidine; CAS 147972-27-8
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(trifluoromethyl)thieno[3,2-d]pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry for identity confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.