Description

3,5-Difluoro-4- Nitrophenol is a fluorinated nitrophenol derivative, a versatile and high-value organic intermediate prized for its unique electronic and steric properties imparted by the fluorine substituents. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) where precise molecular tuning is required. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides, where the difluoro-nitrophenol structure contributes to biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Acts as a monomer or additive to introduce fluorine groups into polymers, improving chemical resistance and surface properties.
• Dye & Pigment Intermediate: Employed in the manufacture of specialized dyes and pigments where fluorine atoms alter color fastness and spectral properties.
• Chemical Research & Development: A valuable reagent for organic synthesis, cross-coupling reactions, and exploring new fluorination methodologies in academic and industrial R&D labs.

Basic Information

Product Name	3,5-Difluoro-4- Nitrophenol
CAS No.	147808-41-1
Molecular Formula	C6H3F2NO3
Molecular Weight	175.09 g/mol
Synonyms	4-Nitro-3,5-difluorophenol; 3,5-Difluoro-4-hydroxy-nitrobenzene; 2,6-Difluoro-4-nitrophenol; Phenol, 3,5-difluoro-4-nitro-; 147808-41-1; 3,5-Difluoro-4-nitrophenol; 4-Nitro-3,5-difluorophenol
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4- Nitrophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.