Description

4-Bromo-1,1-Difluorobut-1-Ene is a versatile organofluorine building block characterized by its reactive bromine and difluoroalkene functionalities. This compound is essential for introducing fluorinated motifs into target molecules, which can dramatically alter their physical, chemical, and biological properties. It is primarily sought after by R&D chemists and process developers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated analogs of drug candidates to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where fluorine incorporation improves efficacy and environmental profile.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and fluorinated materials with unique surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions to create complex, fluorinated organic structures.
• Liquid Crystal & OLED Research: Utilized in the synthesis of fluorinated components for electronic display materials to optimize performance.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	4-Bromo-1,1-Difluorobut-1-Ene
CAS No.	147804-02-2
Molecular Formula	C4H5BrF2
Molecular Weight	171.98 g/mol
Synonyms	1-Butene, 4-bromo-1,1-difluoro-; 4-Bromo-1,1-difluoro-1-butene; 1,1-Difluoro-4-bromo-1-butene; (Difluoromethylene)butyl bromide; 3-Bromopropyl(difluoro)methane
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-1,1-Difluorobut-1-Ene is produced and analyzed under strict quality management protocols. We ensure high-purity standards suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.