Description

ω-Conotoxin Mviic is a potent and selective peptide neurotoxin derived from the venom of marine cone snails. This compound matters as a crucial pharmacological tool for neuroscience research, specifically targeting and blocking N-type voltage-gated calcium channels (Cav2.2). Researchers in pharmaceutical development and academic neuroscience laboratories need it for studying pain pathways, synaptic transmission, and for the development of novel analgesic therapeutics.

Application

• Neuroscience Research: As a selective blocker of N-type calcium channels (Cav2.2) for studying neuronal excitability and neurotransmitter release.
• Pain Pathway Investigation: A key tool in preclinical research for understanding nociceptive signaling and validating targets for non-opioid pain relief.
• Ion Channel Pharmacology: Used in electrophysiology (e.g., patch-clamp) and calcium imaging assays to characterize channel function and screen potential modulators.
• Drug Discovery & Development: Serves as a reference standard and pharmacological probe in the development of novel calcium channel blockers for chronic pain, neuroprotection, and other neurological disorders.
• Synaptic Physiology Studies: Employed to investigate the role of presynaptic calcium channels in synaptic vesicle fusion and plasticity.
• Biochemical Assay Development: Used in binding studies (e.g., radioligand displacement) to assess the affinity of new chemical entities for the Cav2.2 channel.

Basic Information

Product Name	ω-Conotoxin Mviic
CAS No.	147794-23-8
Molecular Formula	C98H150N30O29S7
Molecular Weight	~2639.1 g/mol
Synonyms	ω-Conotoxin MVIIC; Conotoxin MVIIC; ω-Conotoxin MVIIC; ω-CTx-MVIIC; Ctx MVIIC; SNX-230; Calcium channel blocker ω-conotoxin MVIIC; Conus magus toxin MVIIC; Synthetic ω-Conotoxin MVIIC
EINECS	Contact for details

Quality Control

Our ω-Conotoxin Mviic is produced under stringent conditions to ensure high purity and batch-to-batch consistency for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation. A Certificate of Analysis (COA) detailing purity, peptide content, and biological activity (where applicable) is provided with every shipment to support your quality and compliance requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into single-use vials to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Solubility	Soluble in aqueous buffers
Biological Activity	Verified by functional assay (e.g., channel blockade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.