Description

H-Aad(Ome)-Oh Hcl is a protected amino acid derivative, specifically the hydrochloride salt of a methoxy-protected aspartic acid analog. This compound is a crucial building block in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: As a key intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: For the development of novel therapeutic peptides targeting metabolic diseases, oncology, and CNS disorders.
• Bioconjugation: Used in the preparation of peptide-drug conjugates and labeled peptides for diagnostic applications.
• Process Chemistry: Serves as a starting material or intermediate in the scalable manufacturing of peptide-based APIs.
• Biochemical Research: Employed in studies of enzyme-substrate interactions and protein engineering.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to identify new bioactive compounds.

Basic Information

Item	Detail
Product Name	H-Aad(Ome)-Oh Hcl
CAS No.	147780-39-0
Molecular Formula	C6H12ClNO5
Molecular Weight	213.62 g/mol
Synonyms	H-Asp(OMe)-OH·HCl; L-Aspartic acid β-methyl ester hydrochloride; Aspartic acid 4-methyl ester hydrochloride; (S)-2-Amino-4-methoxy-4-oxobutanoic acid hydrochloride; Fmoc-Asp(Ome)-OH precursor; Boc-Asp(Ome)-OH·HCl; Protected aspartic acid methyl ester HCl; β-Methyl L-aspartate hydrochloride
EINECS	Contact for details

Quality Control

Our H-Aad(Ome)-Oh Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.