Description

2,5-Dimethyl-6-Trifluoromethyl-Pyrimidin-4-Ol CAS NO 147750-19-4 is a fluorinated pyrimidine derivative, a high-value organic intermediate prized for its unique structural motif. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceuticals and agrochemicals, where the trifluoromethyl group enhances metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyrimidine core contributes to biological activity.
• Material Science Research: Serves as a precursor for functionalized molecules used in organic electronics and liquid crystal materials.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life science industry.

Basic Information

Product Name	2,5-Dimethyl-6-Trifluoromethyl-Pyrimidin-4-Ol
CAS No.	147750-19-4
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	4-Hydroxy-2,5-dimethyl-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-2,5-dimethylpyrimidin-4-ol; 2,5-Dimethyl-6-trifluoromethyl-4-pyrimidinol; 2,5-Dimethyl-6-(trifluoromethyl)-4(1H)-pyrimidinone; 4-Pyrimidinol, 2,5-dimethyl-6-(trifluoromethyl)-; 147750-19-4
EINECS	Contact for details

Quality Control

Our 2,5-Dimethyl-6-Trifluoromethyl-Pyrimidin-4-Ol is manufactured under strict quality management systems. We offer material suitable for research and development as well as scalable GMP-grade batches for advanced pharmaceutical applications. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided and specifications can be aligned with client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.