Description

H-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-Oh is a synthetic peptide sequence of significant interest in biochemical research and pharmaceutical development. This compound serves as a crucial building block and model substrate for studying protease activity, peptide stability, and structure-activity relationships. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in proteomics, enzymology, and novel therapeutic discovery.

Application

• Biochemical Research: Used as a specific substrate for studying the kinetics and inhibition of various proteases and peptidases.
• Pharmaceutical Development: Acts as an intermediate or reference standard in the discovery and optimization of peptide-based therapeutics.
• Proteomics & Enzymology: Serves as a model peptide to investigate enzyme specificity, protein folding, and peptide degradation pathways.
• Academic Research: Employed in university laboratories for teaching and advanced research in biochemistry and molecular biology.
• Diagnostic Reagent Manufacturing: Can be utilized in the development of enzyme-linked assays and diagnostic kits.
• Bioconjugation Studies: Used in research exploring peptide labeling, tagging, and conjugation techniques due to its reactive functional groups.

Basic Information

Product Name	H-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-Oh
CAS No.	147740-73-6
Molecular Formula	C48H84N12O14S
Molecular Weight	1061.3 g/mol
Synonyms	MLGIIAGKNSG-OH; H-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-OH; Methionyl-leucyl-glycyl-isoleucyl-isoleucyl-alanyl-glycyl-lysyl-asparaginyl-seryl-glycine; Peptide MLGIIAGKNSG; Undecapeptide MLGIIAGKNSG; Acetylated Peptide Substrate (related); Protease Substrate Peptide
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of H-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-Oh undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, amino acid analysis, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.