Description

Connexin 30.3 CAS NO 147652-21-9 is a high-purity chemical compound used in advanced life science research and pharmaceutical development. This specialized molecule is critical for studying intercellular communication and gap junction function, offering researchers a reliable tool for probing complex biological pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, cardiology, and dermatology applications.

Application

• Pharmaceutical Research & Development: Acts as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting gap junction-mediated diseases.
• Life Science Research: Essential for in vitro and in vivo studies investigating the role of specific connexin isoforms in cellular signaling, tissue homeostasis, and disease pathology.
• Biomarker Development: Used in the development and validation of diagnostic assays and biomarkers related to connexin expression and function.
• High-Throughput Screening (HTS): Serves as a compound library standard for screening campaigns aimed at identifying modulators of gap junction activity.
• Academic & Clinical Research: Supports fundamental research in neuroscience (e.g., auditory function, glial networks), cardiology (cardiac conduction), and skin biology.
• Biochemical Reagent: Employed as a critical reagent in enzymatic studies, protein-protein interaction assays, and structural biology projects.

Basic Information

Product Name	Connexin 30.3
CAS No.	147652-21-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GJB4 Protein; Gap Junction β-4 Protein; Connexin-30.3; Cx30.3; GJB4; Gap Junction Protein, Beta 4, 30.3kDa; Connexin 30.3 Peptide; Human Connexin 30.3
EINECS	Contact for details

Quality Control

Every batch of Connexin 30.3 is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for purity (HPLC), identity (Mass Spec, NMR), and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Solubility	Soluble in specific aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.