Description

β-Amyloid (1-9) is a synthetic peptide fragment corresponding to the N-terminal region of the amyloid-beta protein. This compound is a critical research tool for studying the mechanisms of amyloid plaque formation, protein aggregation, and neurodegenerative diseases such as Alzheimer's. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience and therapeutic discovery.

Application

• Neuroscience Research: Fundamental studies on amyloid-beta peptide aggregation kinetics and neurotoxicity.
• Drug Discovery & Screening: Used as a reference standard or target molecule in high-throughput assays to identify potential inhibitors of amyloid aggregation.
• Biomarker Development: Serves as an antigen for the development and calibration of immunoassays (ELISA, Western Blot) designed to detect specific amyloid-beta epitopes.
• Structural Biology: Employed in NMR, X-ray crystallography, and other biophysical studies to elucidate the structure and folding of amyloid-beta fragments.
• Antibody Production: Acts as an immunogen for generating sequence-specific antibodies against the amyloid-beta (1-9) region.
• In Vitro Model Systems: Used to create controlled in vitro models of amyloid fibril formation for mechanistic studies.

Basic Information

Product Name	β-Amyloid (1-9)
CAS No.	147529-30-4
Molecular Formula	C46H67N13O14
Molecular Weight	1026.1 g/mol
Synonyms	Amyloid β-Protein (1-9); Aβ (1-9); Amyloid β-Peptide (1-9); DAEFRHDSG; Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly; β-Amyloid (1-9) peptide; Amyloid β (1-9) fragment
EINECS	Contact for details

Quality Control

Our β-Amyloid (1-9) is produced under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by comprehensive analytical data. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request, supporting compliance with rigorous laboratory standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.