Description

(4'-Fluorobiphenyl-4-Yl)-Methanol is a high-purity fluorinated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, which provides a versatile handle for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorobiphenyl moiety enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for high-performance displays and optical devices.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED fabrication, improving device efficiency and longevity.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, enhancing thermal stability, chemical resistance, and optical properties.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.

Basic Information

Product Name	(4'-Fluorobiphenyl-4-Yl)-Methanol
CAS No.	147497-56-1
Molecular Formula	C₁₃H₁₁FO
Molecular Weight	202.22 g/mol
Synonyms	4'-(Hydroxymethyl)-4-fluorobiphenyl; [1,1'-Biphenyl]-4-methanol, 4'-fluoro-; 4-Fluoro-4'-(hydroxymethyl)biphenyl; (4-Fluorobiphenyl-4'-yl)methanol; p-Fluorophenylbenzyl alcohol; 4'-Fluoro-[1,1'-biphenyl]-4-methanol
EINECS	Contact for details

Quality Control

Our (4'-Fluorobiphenyl-4-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.