Description

4-(Ethylamino)Quinazoline-2-Thiol CAS NO 147408-62-6 is a specialized quinazoline derivative, a high-value intermediate and building block in advanced organic synthesis. Its unique thiol and ethylamino-substituted quinazoline core makes it a critical precursor for developing novel pharmacologically active compounds. This chemical is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential kinase inhibitors, anticancer agents, and other therapeutic small molecules.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators that leverage the quinazoline scaffold.
• Chemical Biology & Proteomics: Serves as a precursor for activity-based probes or affinity tags due to its reactive thiol group.
• Material Science: Investigated as a monomer or additive for creating specialized polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and novel compound library synthesis.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing client-specific advanced intermediates.

Basic Information

Product Name	4-(Ethylamino)Quinazoline-2-Thiol
CAS No.	147408-62-6
Molecular Formula	C11H11N3S
Molecular Weight	217.29 g/mol
Synonyms	2-Mercapto-4-(ethylamino)quinazoline; 4-(Ethylamino)-2-mercaptoquinazoline; 4-Ethylaminoquinazoline-2-thiol; 2-Thiol-4-(ethylamino)quinazoline; Quinazoline-2-thiol, 4-(ethylamino)-; 4-EAQT; 4-Ethylamino-2-quinazolinethiol; 147408-62-6
EINECS	Contact for details

Quality Control

Our production of 4-(Ethylamino)Quinazoline-2-Thiol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.