Description

H-Orn(Aloc)-Oh is a protected derivative of the amino acid ornithine, featuring an allyloxycarbonyl (Aloc) protecting group on the side chain amine. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, specialized amino acid derivatives for advanced drug discovery and development projects.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential construction of peptide chains.
• Pharmaceutical Research: Used in the development of peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as a linker or spacer molecule in the creation of antibody-drug conjugates (ADCs) and other bioconjugates.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify novel bioactive compounds.
• Protecting Group Chemistry: The Aloc group allows for orthogonal deprotection strategies, crucial for synthesizing peptides with multiple functional groups.
• Academic & Industrial R&D: Fundamental reagent for studying protein structure-function relationships and metabolic pathways.

Basic Information

Product Name	H-Orn(Aloc)-Oh
CAS No.	147290-10-6
Molecular Formula	C9H16N2O4
Molecular Weight	216.24 g/mol
Synonyms	Nδ-Alloc-ornithine; N5-(Allyloxycarbonyl)-L-ornithine; (S)-2-Amino-5-((allyloxycarbonyl)amino)pentanoic acid; Alloc-Orn-OH; Fmoc-Orn(Alloc)-OH (precursor); Ornithine(Alloc) derivative; L-Orn(Alloc)-OH; Boc-Orn(Alloc)-OH (precursor)
EINECS	Contact for details

Quality Control

Our H-Orn(Aloc)-Oh is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive spectroscopic identification (NMR, IR, MS). Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.