Description

Norleucine, n-Acetyl-2-Methyl- is a chemically modified amino acid derivative, specifically an N-acetylated form of 2-methylnorleucine. This compound is valued for its role as a specialized building block and intermediate in advanced organic synthesis and peptide research. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, bioactive peptides, and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis to introduce structural modifications, study structure-activity relationships (SAR), or create peptide mimetics.
• Biochemical Research: Acts as a substrate or inhibitor analog in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Synthesis: Employed as a specialized intermediate in the production of complex organic molecules for agrochemicals, materials science, and diagnostics.
• Reference Standard: Suitable for use as a high-purity analytical standard in quality control (QC) and research laboratory settings.

Basic Information

Product Name	Norleucine, n-Acetyl-2-Methyl-
CAS No.	147254-04-4
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	N-Acetyl-2-methylnorleucine; 2-Methyl-N-acetylnorleucine; (2S)-2-Acetamido-2-methylhexanoic acid; N-Acetyl-2-methyl-DL-norleucine; Ac-2-MeNle-OH; 2-Methyl-2-(acetylamino)hexanoic acid
EINECS	Contact for details

Quality Control

Our Norleucine, n-Acetyl-2-Methyl- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and other relevant analytical techniques. Specifications are designed to meet the rigorous demands of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.