Description

Glycyl-Arginyl-Glycyl-Aspartyl-Valyl-Tyrosine is a synthetic hexapeptide sequence with the specific CAS number 147103-09-1. This compound is of significant interest in biochemical research and development due to its role as a specific integrin-binding motif, mimicking key sequences found in extracellular matrix proteins. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and biotechnology sectors for applications in cell adhesion studies, biomaterial functionalization, and targeted drug delivery systems.

Application

• Biomedical Research: Used as a critical ligand in studies of cell adhesion, migration, and signaling pathways mediated by integrin receptors.
• Biomaterial Coating: Functionalizes surfaces of medical implants, scaffolds, and diagnostic devices to promote specific cellular interactions and tissue integration.
• Drug Delivery Systems: Incorporated into nanoparticle or liposome formulations as a targeting moiety for site-specific therapeutic delivery.
• Diagnostic Assay Development: Serves as a capture or detection agent in ELISA and other immunoassays for studying protein-protein interactions.
• Pharmaceutical R&D: Employed in high-throughput screening and as a reference standard in the development of anti-angiogenic or anti-metastatic therapies.
• Cell Culture & Tissue Engineering: Coated on cultureware to create defined, bioactive substrates for stem cell differentiation and 3D tissue model development.

Basic Information

Product Name	Glycyl-Arginyl-Glycyl-Aspartyl-Valyl-Tyrosine
CAS No.	147103-09-1
Molecular Formula	C30H47N11O11
Molecular Weight	713.77 g/mol
Synonyms	GRGDVY; GRGDVY Peptide; Gly-Arg-Gly-Asp-Val-Tyr; Arg-Gly-Asp (RGD) Containing Peptide; Hexapeptide GRGDVY; Integrin Binding Peptide; Cell Adhesion Peptide; Fibronectin Fragment Analog
EINECS	Contact for details

Quality Control

Our Glycyl-Arginyl-Glycyl-Aspartyl-Valyl-Tyrosine is produced under stringent quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Ratio within ±10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.