Description

Alatrofloxacin Mesylate is the water-soluble prodrug of the broad-spectrum fluoroquinolone antibiotic, trovafloxacin. This compound is critical for pharmaceutical research and development, particularly in the formulation of injectable antibiotic therapies. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in developing advanced antibacterial treatments for serious infections.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of the active antibiotic trovafloxacin.
• Injectable Formulation Research: Used in R&D for developing parenteral (injectable) dosage forms due to its enhanced solubility compared to the parent compound.
• Antibacterial Agent Development: A subject of study for creating new fluoroquinolone-based drugs targeting resistant bacterial strains.
• Biochemical Research: Employed in microbiological and pharmacological studies to understand the kinetics and efficacy of prodrug activation.
• Reference Standard: Used as a certified reference material (CRM) in quality control laboratories for analytical method development and validation.

Basic Information

Product Name	Alatrofloxacin Mesylate
CAS No.	146961-77-5
Molecular Formula	C₂₆H₂₈F₃N₅O₉S
Molecular Weight	643.59 g/mol
Synonyms	CP-116,517; Alatrofloxacin methanesulfonate; Trovafloxacin mesylate prodrug; (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, compd. with methanesulfonic acid (1:1); Trovafloxacin alaninyl hydrochloride (obsolete nomenclature).
EINECS	Contact for details

Quality Control

Our Alatrofloxacin Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets high-grade standards suitable for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.